The CYP1A2 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CP12, and CYP1A2. This antibody recognizes Human antigen. The CYP1A2 Antibody has been validated for the following applications: ELISA, and Western Blot.
Description
This gene encodes a member of the cytochrome P450
superfamily of enzymes. The cytochrome P450 proteins are
monooxygenases which catalyze many reactions involved in drug
metabolism and synthesis of cholesterol, steroids and other lipids.
The protein encoded by this gene localizes to the endoplasmic
reticulum and its expression is induced by some polycyclic aromatic
hydrocarbons (PAHs), some of which are found in cigarette smoke.
The enzyme's endogenous substrate is unknown; however, it is able
to metabolize some PAHs to carcinogenic intermediates. Other
xenobiotic substrates for this enzyme include caffeine, aflatoxin
B1, and acetaminophen. The transcript from this gene contains four
Alu sequences flanked by direct repeats in the 3' untranslated
region